Practical
Aim:
To determine the effect of acidity on the neutralisation of
antacid tablets
Hypothesis:
Independent variable:
Dependent variable:
Constant variables:
Equipment:
1 x measuring cylinder
2 x 150 mL beaker
2 x stopwatch
2 x antacid tablets
pH paper and key
10mL 1M Hydrochloric acid (HCl)
10mL Vinegar (Acetic acid)
100mL tap water
Risk management:
Method:
- Dilute
the hydrochloric acid in 50mL of water
- …
- Table:
- Graph:
Administration of drugs
• There
are many ways that drugs can be administered:
– By
mouth
– By
inhalation (very fast absorption into nasal membranes)
– Skin
or dermal patches (slow absorption)
– Creams
– Suppositories
by rectum or vagina
– Injection
into blood or tissue
– Ear
or eye drops onto affected tissue
Water-soluble v Fat-soluble
|
Water-soluble
|
Fat-soluble
|
|
Vitamins A, D, E, K
Can be stored in body tissue
Can be toxic if too much is taken
|
B1, B2, Niacin, B6, pantothenic acid, biotin, B12, folate,
vitamin C
Excess amounts will be excreted in urine
|
Review of Objectives
• Explain
why a knowledge of the solubility of materials can be used to design drugs for
specific tasks
• Account
for the absorption of a drug and its action on/in the body in terms of its
solubility
• Identify
that the manner of administration of a drug may be related to its solubility
• Identify
vitamins that are water soluble and those that are fat-soluble
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